Requirement for Chloride Channel Function during the Hepatitis C Virus Life Cycle

Hepatocytes express an array of plasma membrane and intracellular ion channels, yet their role during the hepatitis C virus (HCV) life cycle remains largely undefined. Here, we show that HCV increases intracellular hepatic chloride (Cl(−)) influx that can be inhibited by selective Cl(−) channel bloc...

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Detalles Bibliográficos
Autores principales: Igloi, Zsofia, Mohl, Bjorn-Patrick, Lippiat, Jonathan D., Harris, Mark, Mankouri, Jamel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403416/
https://www.ncbi.nlm.nih.gov/pubmed/25609806
http://dx.doi.org/10.1128/JVI.02946-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403416/
https://www.ncbi.nlm.nih.gov/pubmed/25609806
http://dx.doi.org/10.1128/JVI.02946-14

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