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Requirement for Chloride Channel Function during the Hepatitis C Virus Life Cycle
Hepatocytes express an array of plasma membrane and intracellular ion channels, yet their role during the hepatitis C virus (HCV) life cycle remains largely undefined. Here, we show that HCV increases intracellular hepatic chloride (Cl(−)) influx that can be inhibited by selective Cl(−) channel bloc...
Autores principales: | Igloi, Zsofia, Mohl, Bjorn-Patrick, Lippiat, Jonathan D., Harris, Mark, Mankouri, Jamel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403416/ https://www.ncbi.nlm.nih.gov/pubmed/25609806 http://dx.doi.org/10.1128/JVI.02946-14 |
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