Mitochondrial function provides instructive signals for activation-induced B-cell fates

During immune reactions, functionally distinct B-cell subsets are generated by stochastic processes, including class-switch recombination (CSR) and plasma cell differentiation (PCD). In this study, we show a strong association between individual B-cell fates and mitochondrial functions. CSR occurs s...

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Detalles Bibliográficos
Autores principales: Jang, Kyoung-Jin, Mano, Hiroto, Aoki, Koji, Hayashi, Tatsunari, Muto, Akihiko, Nambu, Yukiko, Takahashi, Katsu, Itoh, Katsuhiko, Taketani, Shigeru, Nutt, Stephen L., Igarashi, Kazuhiko, Shimizu, Akira, Sugai, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403446/
https://www.ncbi.nlm.nih.gov/pubmed/25857523
http://dx.doi.org/10.1038/ncomms7750

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