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The significance of combining VEGFA, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab

Targeting angiogenesis through inhibition of the vascular endothelial growth factor (VEGF) pathway has been successful in the treatment of late stage colorectal cancer. However, not all patients benefit from inhibition of VEGF. Ras status is a powerful biomarker for response to anti-epidermal growth...

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Detalles Bibliográficos
Autores principales: Zhang, Shu-Dong, McCrudden, Cian M, Meng, Chen, Lin, Yao, Kwok, Hang Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403689/
https://www.ncbi.nlm.nih.gov/pubmed/25926745
http://dx.doi.org/10.2147/OTT.S80518