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The significance of combining VEGFA, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab
Targeting angiogenesis through inhibition of the vascular endothelial growth factor (VEGF) pathway has been successful in the treatment of late stage colorectal cancer. However, not all patients benefit from inhibition of VEGF. Ras status is a powerful biomarker for response to anti-epidermal growth...
Autores principales: | Zhang, Shu-Dong, McCrudden, Cian M, Meng, Chen, Lin, Yao, Kwok, Hang Fai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403689/ https://www.ncbi.nlm.nih.gov/pubmed/25926745 http://dx.doi.org/10.2147/OTT.S80518 |
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