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Human pancreatic cancer stem cells are sensitive to dual inhibition of IGF-IR and ErbB receptors

BACKGROUND: Pancreatic ductal adenocarcinoma is a particularly challenging malignancy characterized by poor responsiveness to conventional chemotherapy. Although this tumor frequently overexpresses or possesses constitutively activated variants of IGF-IR and EGFR/Her-2, clinical trials using inhibit...

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Detalles Bibliográficos
Autores principales:	Urtasun, Nerea, Vidal-Pla, Anna, Pérez-Torras, Sandra, Mazo, Adela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403908/ https://www.ncbi.nlm.nih.gov/pubmed/25886138 http://dx.doi.org/10.1186/s12885-015-1249-2

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