Cargando…

Wear Particles Derived from Metal Hip Implants Induce the Generation of Multinucleated Giant Cells in a 3-Dimensional Peripheral Tissue-Equivalent Model

Multinucleate giant cells (MGCs) are formed by the fusion of 5 to 15 monocytes or macrophages. MGCs can be generated by hip implants at the site where the metal surface of the device is in close contact with tissue. MGCs play a critical role in the inflammatory processes associated with adverse even...

Descripción completa

Detalles Bibliográficos
Autores principales: Dutta, Debargh K., Potnis, Pushya A., Rhodes, Kelly, Wood, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403993/
https://www.ncbi.nlm.nih.gov/pubmed/25894745
http://dx.doi.org/10.1371/journal.pone.0124389