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Wear Particles Derived from Metal Hip Implants Induce the Generation of Multinucleated Giant Cells in a 3-Dimensional Peripheral Tissue-Equivalent Model

Multinucleate giant cells (MGCs) are formed by the fusion of 5 to 15 monocytes or macrophages. MGCs can be generated by hip implants at the site where the metal surface of the device is in close contact with tissue. MGCs play a critical role in the inflammatory processes associated with adverse even...

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Detalles Bibliográficos
Autores principales:	Dutta, Debargh K., Potnis, Pushya A., Rhodes, Kelly, Wood, Steven C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403993/ https://www.ncbi.nlm.nih.gov/pubmed/25894745 http://dx.doi.org/10.1371/journal.pone.0124389

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