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Increased MicroRNA-34b and -34c Predominantly Expressed in Stromal Tissues Is Associated with Poor Prognosis in Human Colon Cancer

The microRNA-34 family (miR-34a, -34b and -34c) have been reported to be tumor suppressor microRNAs (miRNAs) that are regulated by the TP53 and DNA hypermethylation. However, the expression, regulation, and prognostic value of the miR-34 family have not been systematically studied in colon cancer. T...

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Detalles Bibliográficos
Autores principales: Hiyoshi, Yukiharu, Schetter, Aaron J., Okayama, Hirokazu, Inamura, Kentaro, Anami, Katsuhiro, Nguyen, Giang H., Horikawa, Izumi, Hawkes, Jason E., Bowman, Elise D., Leung, Suet Yi, Harris, Curtis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404052/
https://www.ncbi.nlm.nih.gov/pubmed/25894979
http://dx.doi.org/10.1371/journal.pone.0124899

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