Cargando…

ZEB1 transcriptionally regulated carbonic anhydrase 9 mediates the chemoresistance of tongue cancer via maintaining intracellular pH

BACKGROUND: Chemoresistance is a major obstacle in successfully treating cancers, and the mechanisms responsible for drug resistance are still far from understood. Carbonic anhydrase 9 (CA9) has been shown to be upregulated in the drug-resistant tongue cancer cell line Tca8113/PYM and to be associat...

Descripción completa

Detalles Bibliográficos
Autores principales: Zheng, Guopei, Peng, Cong, Jia, Xiaoting, Gu, Yixue, Zhang, Zhijie, Deng, Yingen, Wang, Chengkun, Li, Nan, Yin, Jiang, Liu, Xiaorong, Lu, Minying, Tang, Hailin, He, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404088/
https://www.ncbi.nlm.nih.gov/pubmed/25890268
http://dx.doi.org/10.1186/s12943-015-0357-6