Advanced age is associated with worsened outcomes and a unique genomic response in severely injured patients with hemorrhagic shock

INTRODUCTION: We wished to characterize the relationship of advanced age to clinical outcomes and to transcriptomic responses after severe blunt traumatic injury with hemorrhagic shock. METHODS: We performed epidemiological, cytokine, and transcriptomic analyses on a prospective, multi-center cohort...

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Detalles Bibliográficos
Autores principales: Vanzant, Erin L, Hilton, Rachael E, Lopez, Cecilia M, Zhang, Jianyi, Ungaro, Ricardo F, Gentile, Lori F, Szpila, Benjamin E, Maier, Ronald V, Cuschieri, Joseph, Bihorac, Azra, Leeuwenburgh, Christiaan, Moore, Frederick A, Baker, Henry V, Moldawer, Lyle L, Brakenridge, Scott C, Efron, Philip A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404112/
https://www.ncbi.nlm.nih.gov/pubmed/25880307
http://dx.doi.org/10.1186/s13054-015-0788-x

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