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Defining window-boundaries for genomic analyses using smoothing spline techniques

BACKGROUND: High-density genomic data is often analyzed by combining information over windows of adjacent markers. Interpretation of data grouped in windows versus at individual locations may increase statistical power, simplify computation, reduce sampling noise, and reduce the total number of test...

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Detalles Bibliográficos
Autores principales: Beissinger, Timothy M, Rosa, Guilherme JM, Kaeppler, Shawn M, Gianola, Daniel, de Leon, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404117/
https://www.ncbi.nlm.nih.gov/pubmed/25928167
http://dx.doi.org/10.1186/s12711-015-0105-9