A Functional Interplay between Human Immunodeficiency Virus Type 1 Protease Residues 77 and 93 Involved in Differential Regulation of Precursor Autoprocessing and Mature Protease Activity

HIV-1 protease (PR) is a viral enzyme vital to the production of infectious virions. It is initially synthesized as part of the Gag-Pol polyprotein precursor in the infected cell. The free mature PR is liberated as a result of precursor autoprocessing upon virion release. We previously described a m...

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Detalles Bibliográficos
Autores principales: Counts, Christopher J., Ho, P. Shing, Donlin, Maureen J., Tavis, John E., Chen, Chaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404164/
https://www.ncbi.nlm.nih.gov/pubmed/25893662
http://dx.doi.org/10.1371/journal.pone.0123561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404164/
https://www.ncbi.nlm.nih.gov/pubmed/25893662
http://dx.doi.org/10.1371/journal.pone.0123561

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