Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds

Development of resistance against current antimalarial drugs necessitates the search for novel drugs that interact with different targets and have distinct mechanisms of action. Malaria parasites depend upon high levels of glucose uptake followed by inefficient metabolic utilization via the glycolyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Ortiz, Diana, Guiguemde, W. Armand, Johnson, Alex, Elya, Carolyn, Anderson, Johanna, Clark, Julie, Connelly, Michele, Yang, Lei, Min, Jaeki, Sato, Yuko, Guy, R. Kiplin, Landfear, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404333/
https://www.ncbi.nlm.nih.gov/pubmed/25894322
http://dx.doi.org/10.1371/journal.pone.0123598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404333/
https://www.ncbi.nlm.nih.gov/pubmed/25894322
http://dx.doi.org/10.1371/journal.pone.0123598

Ejemplares similares