Malaria real-time PCR: correlation with clinical presentation

Among 112 patients infected only by Plasmodium falciparum, WHO criteria of severity were compared with parasite load assessed by microscopy and quantitative PCR. Clinical severity was significantly correlated with higher parasite load as determined by microscopy (p < 0.001) and by PCR (p < 0.0...

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Autores principales: Dormond, L., Jaton, K., de Vallière, S., Genton, B., Greub, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
New Technologies for Infectious and Tropical Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404418/
https://www.ncbi.nlm.nih.gov/pubmed/25905022
http://dx.doi.org/10.1016/j.nmni.2015.02.004
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author Dormond, L.
Jaton, K.
de Vallière, S.
Genton, B.
Greub, G.
author_facet Dormond, L.
Jaton, K.
de Vallière, S.
Genton, B.
Greub, G.
author_sort Dormond, L.
collection PubMed
description Among 112 patients infected only by Plasmodium falciparum, WHO criteria of severity were compared with parasite load assessed by microscopy and quantitative PCR. Clinical severity was significantly correlated with higher parasite load as determined by microscopy (p < 0.001) and by PCR (p < 0.001). Hence, quantitative PCR might be useful to predict outcome.
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spelling pubmed-44044182015-04-22 Malaria real-time PCR: correlation with clinical presentation Dormond, L. Jaton, K. de Vallière, S. Genton, B. Greub, G. New Microbes New Infect New Technologies for Infectious and Tropical Diseases Among 112 patients infected only by Plasmodium falciparum, WHO criteria of severity were compared with parasite load assessed by microscopy and quantitative PCR. Clinical severity was significantly correlated with higher parasite load as determined by microscopy (p < 0.001) and by PCR (p < 0.001). Hence, quantitative PCR might be useful to predict outcome. Elsevier 2015-02-28 /pmc/articles/PMC4404418/ /pubmed/25905022 http://dx.doi.org/10.1016/j.nmni.2015.02.004 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle New Technologies for Infectious and Tropical Diseases
Dormond, L.
Jaton, K.
de Vallière, S.
Genton, B.
Greub, G.
Malaria real-time PCR: correlation with clinical presentation
title Malaria real-time PCR: correlation with clinical presentation
title_full Malaria real-time PCR: correlation with clinical presentation
title_fullStr Malaria real-time PCR: correlation with clinical presentation
title_full_unstemmed Malaria real-time PCR: correlation with clinical presentation
title_short Malaria real-time PCR: correlation with clinical presentation
title_sort malaria real-time pcr: correlation with clinical presentation
topic New Technologies for Infectious and Tropical Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404418/
https://www.ncbi.nlm.nih.gov/pubmed/25905022
http://dx.doi.org/10.1016/j.nmni.2015.02.004
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