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A method to associate all possible combinations of genetic and environmental factors using GxE landscape plot

Genome-wide association studies (GWAS) and linkage analysis has identified many single nucleotide polymorphisms (SNPs) related to disease. There are many unknown SNPs whose minor allele frequencies (MAFs) as low as 0.005 having intermediate effects with odds ratio between 1.5~3.0. Low frequency vari...

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Detalles Bibliográficos
Autores principales: Nagaie, Satoshi, Ogishima, Soichi, Nakaya, Jun, Tanaka, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404419/
https://www.ncbi.nlm.nih.gov/pubmed/25914450
http://dx.doi.org/10.6026/97320630011161