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Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value
BACKGROUND: Systematic analysis of cancer gene-expression patterns using high-throughput transcriptional profiling technologies has led to the discovery and publication of hundreds of gene-expression signatures. However, few public signature values have been cross-validated over multiple studies for...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404582/ https://www.ncbi.nlm.nih.gov/pubmed/25886164 http://dx.doi.org/10.1186/s12885-015-1102-7 |