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CCR5 facilitates endothelial progenitor cell recruitment and promotes the stabilization of atherosclerotic plaques in ApoE(−/−) mice

INTRODUCTION: Unstable atherosclerotic plaques are prone to rupture, which leads to atherothrombosis. Endothelial progenitor cells (EPCs) are bone marrow-derived precursor cells that may repair vascular injury in atherosclerosis. Chemokine (C-C motif) receptor 5 (CCR5) promotes mobilization of EPCs....

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Detalles Bibliográficos
Autores principales: Zhang, Zhongwen, Dong, Jianjun, Lobe, Corrinne G, Gong, Peiyun, Liu, Ju, Liao, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404610/
https://www.ncbi.nlm.nih.gov/pubmed/25889019
http://dx.doi.org/10.1186/s13287-015-0026-0