Non-crossover gene conversions show strong GC bias and unexpected clustering in humans

Although the past decade has seen tremendous progress in our understanding of fine-scale recombination, little is known about non-crossover (NCO) gene conversion. We report the first genome-wide study of NCO events in humans. Using SNP array data from 98 meioses, we identified 103 sites affected by...

Descripción completa

Detalles Bibliográficos
Autores principales: Williams, Amy L, Genovese, Giulio, Dyer, Thomas, Altemose, Nicolas, Truax, Katherine, Jun, Goo, Patterson, Nick, Myers, Simon R, Curran, Joanne E, Duggirala, Ravi, Blangero, John, Reich, David, Przeworski, Molly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404656/
https://www.ncbi.nlm.nih.gov/pubmed/25806687
http://dx.doi.org/10.7554/eLife.04637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404656/
https://www.ncbi.nlm.nih.gov/pubmed/25806687
http://dx.doi.org/10.7554/eLife.04637

Ejemplares similares