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MeCP2 plays an analgesic role in pain transmission through regulating CREB / miR-132 pathway
BACKGROUND: The Methyl CpG binding protein 2 gene (MeCP2 gene) encodes a critical transcriptional repressor and is widely expressed in mammalian neurons. MeCP2 plays a critical role in neuronal differentiation, neural development, and synaptic plasticity. Mutations and duplications of the human MECP...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404689/ https://www.ncbi.nlm.nih.gov/pubmed/25885346 http://dx.doi.org/10.1186/s12990-015-0015-4 |