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MeCP2 plays an analgesic role in pain transmission through regulating CREB / miR-132 pathway

BACKGROUND: The Methyl CpG binding protein 2 gene (MeCP2 gene) encodes a critical transcriptional repressor and is widely expressed in mammalian neurons. MeCP2 plays a critical role in neuronal differentiation, neural development, and synaptic plasticity. Mutations and duplications of the human MECP...

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Detalles Bibliográficos
Autores principales: Zhang, Ran, Huang, Min, Cao, Zhijuan, Qi, Jieyu, Qiu, Zilong, Chiang, Li-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404689/
https://www.ncbi.nlm.nih.gov/pubmed/25885346
http://dx.doi.org/10.1186/s12990-015-0015-4

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