Cargando…
MeCP2 plays an analgesic role in pain transmission through regulating CREB / miR-132 pathway
BACKGROUND: The Methyl CpG binding protein 2 gene (MeCP2 gene) encodes a critical transcriptional repressor and is widely expressed in mammalian neurons. MeCP2 plays a critical role in neuronal differentiation, neural development, and synaptic plasticity. Mutations and duplications of the human MECP...
Autores principales: | Zhang, Ran, Huang, Min, Cao, Zhijuan, Qi, Jieyu, Qiu, Zilong, Chiang, Li-Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404689/ https://www.ncbi.nlm.nih.gov/pubmed/25885346 http://dx.doi.org/10.1186/s12990-015-0015-4 |
Ejemplares similares
-
Tau overexpression impairs neuronal endocytosis by decreasing the GTPase dynamin 1 through the miR‐132/MeCP2 pathway
por: Xie, Ao‐Ji, et al.
Publicado: (2019) -
Rett mutations attenuate phase separation of MeCP2
por: Fan, Chunyan, et al.
Publicado: (2020) -
MeCP2 mediates transgenerational transmission of chronic pain
por: Tao, Wenjuan, et al.
Publicado: (2020) -
Detrusor Induction of miR-132/212 following Bladder Outlet Obstruction: Association with MeCP2 Repression and Cell Viability
por: Sadegh, Mardjaneh Karbalaei, et al.
Publicado: (2015) -
MeCP2 and Chromatin Compartmentalization
por: Schmidt, Annika, et al.
Publicado: (2020)