Cargando…
RhoGDI2 up-regulates P-glycoprotein expression via Rac1 in gastric cancer cells
Multidrug resistance (MDR) is a major clinical obstacle in treatment of gastric cancer. Previously, using 2D electrophoresis-mass spectrometry, we identified RhoGDI2 as a contributor to 5-FU resistance in colon cancer cells, and also confer gastric cancer cells resistance to 5-FU. Here, we reported...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404694/ https://www.ncbi.nlm.nih.gov/pubmed/25901126 http://dx.doi.org/10.1186/s12935-015-0190-4 |