Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18

Positron emission tomography (PET) is unique in that it allows quantification of biochemical processes in vivo, but difficulties with preparing suitably labelled radiotracers limit its scientific and diagnostic applications. Aromatic [(18)F]fluorination of drug-like small molecules is particularly c...

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Detalles Bibliográficos
Autores principales: Sander, Kerstin, Gendron, Thibault, Yiannaki, Elena, Cybulska, Klaudia, Kalber, Tammy L., Lythgoe, Mark F., Årstad, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404714/
https://www.ncbi.nlm.nih.gov/pubmed/25898175
http://dx.doi.org/10.1038/srep09941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404714/
https://www.ncbi.nlm.nih.gov/pubmed/25898175
http://dx.doi.org/10.1038/srep09941

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