In situ immunization via non-surgical ablation to prevent local and distant tumor recurrence

Host immunities are induced during cryoablation or oncolytic adenovirus therapy when the entire repertoire of tumor associated antigens (TAA) is released. Local and systemic protection is enhanced by the combined treatment with toll-like receptor agonist or immune stimulating cytokines. Non-surgical...

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Autores principales: Veenstra, Jesse J, Gibson, Heather M, Freytag, Svend, Littrup, Peter J, Wei, Wei-Zen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404795/
https://www.ncbi.nlm.nih.gov/pubmed/25949901
http://dx.doi.org/10.4161/2162402X.2014.989762
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author Veenstra, Jesse J
Gibson, Heather M
Freytag, Svend
Littrup, Peter J
Wei, Wei-Zen
author_facet Veenstra, Jesse J
Gibson, Heather M
Freytag, Svend
Littrup, Peter J
Wei, Wei-Zen
author_sort Veenstra, Jesse J
collection PubMed
description Host immunities are induced during cryoablation or oncolytic adenovirus therapy when the entire repertoire of tumor associated antigens (TAA) is released. Local and systemic protection is enhanced by the combined treatment with toll-like receptor agonist or immune stimulating cytokines. Non-surgical tumor ablation is an effective platform for in situ immunization.
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spelling pubmed-44047952016-02-03 In situ immunization via non-surgical ablation to prevent local and distant tumor recurrence Veenstra, Jesse J Gibson, Heather M Freytag, Svend Littrup, Peter J Wei, Wei-Zen Oncoimmunology Author's View Host immunities are induced during cryoablation or oncolytic adenovirus therapy when the entire repertoire of tumor associated antigens (TAA) is released. Local and systemic protection is enhanced by the combined treatment with toll-like receptor agonist or immune stimulating cytokines. Non-surgical tumor ablation is an effective platform for in situ immunization. Taylor & Francis 2015-04-02 /pmc/articles/PMC4404795/ /pubmed/25949901 http://dx.doi.org/10.4161/2162402X.2014.989762 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Veenstra, Jesse J
Gibson, Heather M
Freytag, Svend
Littrup, Peter J
Wei, Wei-Zen
In situ immunization via non-surgical ablation to prevent local and distant tumor recurrence
title In situ immunization via non-surgical ablation to prevent local and distant tumor recurrence
title_full In situ immunization via non-surgical ablation to prevent local and distant tumor recurrence
title_fullStr In situ immunization via non-surgical ablation to prevent local and distant tumor recurrence
title_full_unstemmed In situ immunization via non-surgical ablation to prevent local and distant tumor recurrence
title_short In situ immunization via non-surgical ablation to prevent local and distant tumor recurrence
title_sort in situ immunization via non-surgical ablation to prevent local and distant tumor recurrence
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404795/
https://www.ncbi.nlm.nih.gov/pubmed/25949901
http://dx.doi.org/10.4161/2162402X.2014.989762
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