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Recombinant Mutated Human TNF in Combination with Chemotherapy for Stage IIIB/IV Non-Small Cell Lung Cancer: A Randomized, Phase III Study

Tumor necrosis factor (TNF), an anti-angiogenic agent in cancer treatment, is limited to isolated limb perfusion due to systemic toxicities. We previously prepared a TNF mutant (rmhTNF) that significantly improved responses in lung cancer patients and exhibited a promising safety profile in phase I...

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Detalles Bibliográficos
Autores principales:	Ma, Xiaowen, Song, Yang, Zhang, Kuo, Shang, Lei, Gao, Yuan, Zhang, Wei, Xue, Xiaochang, Jia, Huimin, Geng, Jian, Zhou, Wei, Dang, Yazheng, Li, Enxiao, Ti, Xinyu, Fan, Fulin, Zhang, Yingqi, Li, Meng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404801/ https://www.ncbi.nlm.nih.gov/pubmed/25897826 http://dx.doi.org/10.1038/srep09918

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