CD4(+) T cell plasticity engenders robust immunity in response to cytokine therapy

CD4(+) T cells represent an entire arm of the immune system that has hitherto been incompletely understood, but their potential to act as both helper and effector may make them optimal protagonists in immunotherapeutic approaches to treat cancer. Cytokine therapy can activate this population in a ma...

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Detalles Bibliográficos
Autores principales: Nelles, Megan E, Paige, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404832/
https://www.ncbi.nlm.nih.gov/pubmed/25949915
http://dx.doi.org/10.4161/2162402X.2014.994370
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author Nelles, Megan E
Paige, Christopher J
author_facet Nelles, Megan E
Paige, Christopher J
author_sort Nelles, Megan E
collection PubMed
description CD4(+) T cells represent an entire arm of the immune system that has hitherto been incompletely understood, but their potential to act as both helper and effector may make them optimal protagonists in immunotherapeutic approaches to treat cancer. Cytokine therapy can activate this population in a manner that ensures maximal diversification of effector function for a robust immune response.
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spelling pubmed-44048322016-01-22 CD4(+) T cell plasticity engenders robust immunity in response to cytokine therapy Nelles, Megan E Paige, Christopher J Oncoimmunology Author's View CD4(+) T cells represent an entire arm of the immune system that has hitherto been incompletely understood, but their potential to act as both helper and effector may make them optimal protagonists in immunotherapeutic approaches to treat cancer. Cytokine therapy can activate this population in a manner that ensures maximal diversification of effector function for a robust immune response. Taylor & Francis 2015-01-22 /pmc/articles/PMC4404832/ /pubmed/25949915 http://dx.doi.org/10.4161/2162402X.2014.994370 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Nelles, Megan E
Paige, Christopher J
CD4(+) T cell plasticity engenders robust immunity in response to cytokine therapy
title CD4(+) T cell plasticity engenders robust immunity in response to cytokine therapy
title_full CD4(+) T cell plasticity engenders robust immunity in response to cytokine therapy
title_fullStr CD4(+) T cell plasticity engenders robust immunity in response to cytokine therapy
title_full_unstemmed CD4(+) T cell plasticity engenders robust immunity in response to cytokine therapy
title_short CD4(+) T cell plasticity engenders robust immunity in response to cytokine therapy
title_sort cd4(+) t cell plasticity engenders robust immunity in response to cytokine therapy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404832/
https://www.ncbi.nlm.nih.gov/pubmed/25949915
http://dx.doi.org/10.4161/2162402X.2014.994370
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