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NKT cell-targeted vaccination plus anti-4–1BB antibody generates persistent CD8 T cell immunity against B cell lymphoma

Harnessing the immune adjuvant properties of natural killer T (NKT) cells is an effective strategy to generate anticancer immunity. The objective of this study was to increase the potency and durability of vaccine-induced immunity against B cell lymphoma by combining α-galactosylceramide (α-GalCer)-...

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Detalles Bibliográficos
Autores principales: Kobayashi, Takumi, Doff, Brianna L, Rearden, Rory C, Leggatt, Graham R, Mattarollo, Stephen R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404843/
https://www.ncbi.nlm.nih.gov/pubmed/25949907
http://dx.doi.org/10.4161/2162402X.2014.990793