The discovery of dendritic spines by Cajal

Dendritic spines were considered an artifact of the Golgi method until a brash Spanish histologist, Santiago Ramón y Cajal, bet his scientific career arguing that they were indeed real, correctly deducing their key role in mediating synaptic connectivity. This article reviews the historical context...

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Detalles Bibliográficos
Autor principal: Yuste, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404913/
https://www.ncbi.nlm.nih.gov/pubmed/25954162
http://dx.doi.org/10.3389/fnana.2015.00018
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author Yuste, Rafael
author_facet Yuste, Rafael
author_sort Yuste, Rafael
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description Dendritic spines were considered an artifact of the Golgi method until a brash Spanish histologist, Santiago Ramón y Cajal, bet his scientific career arguing that they were indeed real, correctly deducing their key role in mediating synaptic connectivity. This article reviews the historical context of the discovery of spines and the reasons behind Cajal's obsession with them, all the way till his deathbed.
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spelling pubmed-44049132015-05-07 The discovery of dendritic spines by Cajal Yuste, Rafael Front Neuroanat Neuroscience Dendritic spines were considered an artifact of the Golgi method until a brash Spanish histologist, Santiago Ramón y Cajal, bet his scientific career arguing that they were indeed real, correctly deducing their key role in mediating synaptic connectivity. This article reviews the historical context of the discovery of spines and the reasons behind Cajal's obsession with them, all the way till his deathbed. Frontiers Media S.A. 2015-04-21 /pmc/articles/PMC4404913/ /pubmed/25954162 http://dx.doi.org/10.3389/fnana.2015.00018 Text en Copyright © 2015 Yuste. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Yuste, Rafael
The discovery of dendritic spines by Cajal
title The discovery of dendritic spines by Cajal
title_full The discovery of dendritic spines by Cajal
title_fullStr The discovery of dendritic spines by Cajal
title_full_unstemmed The discovery of dendritic spines by Cajal
title_short The discovery of dendritic spines by Cajal
title_sort discovery of dendritic spines by cajal
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404913/
https://www.ncbi.nlm.nih.gov/pubmed/25954162
http://dx.doi.org/10.3389/fnana.2015.00018
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