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Cancer stem cell vaccine inhibits metastases of primary tumors and induces humoral immune responses against cancer stem cells
The inability to target cancer stem cells (CSC) may be a significant factor contributing to treatment failure. We have developed a strategy to target the CSC populations in melanoma and squamous cell carcinoma using CSC lysate-pulsed dendritic cells (DCs). The CSC-DC vaccine was administered in the...
Autores principales: | Lu, Lin, Tao, Huimin, Chang, Alfred E, Hu, Yangyang, Shu, Guoshun, Chen, Quanning, Egenti, Martin, Owen, John, Moyer, Jeffrey S, Prince, Mark EP, Huang, Shiang, Wicha, Max S, Xia, Jian-Chuan, Li, Qiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404925/ https://www.ncbi.nlm.nih.gov/pubmed/25949905 http://dx.doi.org/10.4161/2162402X.2014.990767 |
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