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Chronic L-DOPA induces hyperactivity, normalization of gait and dyskinetic behavior in MitoPark mice

Dopamine (DA) replacement therapy continues to be the gold standard treatment for Parkinson's disease (PD), as it improves key motor symptoms including bradykinesia and gait disturbances. With time, treatment induces side effects in the majority of patients, known as L-DOPA-induced dyskinesia (...

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Detalles Bibliográficos
Autores principales: Gellhaar, S, Marcellino, D, Abrams, M B, Galter, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405092/
https://www.ncbi.nlm.nih.gov/pubmed/25752644
http://dx.doi.org/10.1111/gbb.12210

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