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Chronic L-DOPA induces hyperactivity, normalization of gait and dyskinetic behavior in MitoPark mice
Dopamine (DA) replacement therapy continues to be the gold standard treatment for Parkinson's disease (PD), as it improves key motor symptoms including bradykinesia and gait disturbances. With time, treatment induces side effects in the majority of patients, known as L-DOPA-induced dyskinesia (...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405092/ https://www.ncbi.nlm.nih.gov/pubmed/25752644 http://dx.doi.org/10.1111/gbb.12210 |