Cargando…
Central Role of Gimap5 in Maintaining Peripheral Tolerance and T Cell Homeostasis in the Gut
Inflammatory bowel disease (IBD) including Crohn's disease and ulcerative colitis is often precipitated by an abnormal immune response to microbiota due to host genetic aberrancies. Recent studies highlight the importance of the host genome and microflora interactions in the pathogenesis of muc...
Autores principales: | Endale, Mehari, Aksoylar, H. Ibrahim, Hoebe, Kasper |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405212/ https://www.ncbi.nlm.nih.gov/pubmed/25944983 http://dx.doi.org/10.1155/2015/436017 |
Ejemplares similares
-
Gimap5-dependent inactivation of GSK3β is required for CD4(+) T cell homeostasis and prevention of immune pathology
por: Patterson, Andrew R., et al.
Publicado: (2018) -
GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension
por: Drzewiecki, Kaela, et al.
Publicado: (2021) -
GIMAP5 Deficiency Is Associated with Increased AKT Activity in T Lymphocytes
por: Chen, Xi-Lin, et al.
Publicado: (2015) -
TCR and IL-7 Signaling Are Altered in the Absence of Functional GTPase of the Immune Associated Nucleotide Binding Protein 5 (GIMAP5)
por: Chen, Xi-Lin, et al.
Publicado: (2016) -
GIMAP Proteins in T-Lymphocytes
por: Filén, Sanna, et al.
Publicado: (2010)