STEC:O111-HUS complicated by acute encephalopathy in a young girl was successfully treated with a set of hemodiafiltration, steroid pulse, and soluble thrombomodulin under plasma exchange

We report a 14-year-old girl, who developed shigatoxin-producing E. coli (STEC)-HUS complicated by encephalopathy. She was successfully treated with hemodiafiltration, high-dose methylprednisolone pulse therapy, and soluble recombinant thrombomodulin under plasma exchange. von Willebrand factor mult...

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Detalles Bibliográficos
Autores principales: Yada, Noritaka, Fujioka, Masayuki, Bennett, Charles L, Inoki, Kazuya, Miki, Toyokazu, Watanabe, Akihiko, Yoshida, Toshiko, Hayakawa, Masaki, Matsumoto, Masanori, Fujimura, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405303/
https://www.ncbi.nlm.nih.gov/pubmed/25914810
http://dx.doi.org/10.1002/ccr3.196
Descripción
Sumario:We report a 14-year-old girl, who developed shigatoxin-producing E. coli (STEC)-HUS complicated by encephalopathy. She was successfully treated with hemodiafiltration, high-dose methylprednisolone pulse therapy, and soluble recombinant thrombomodulin under plasma exchange. von Willebrand factor multimers analysis provides potential insights into how the administered therapies might facilitate successful treatment of STEC-HUS.

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