Finding the elusive and causative autoantibody: An atypical case of autoimmune hemolytic anemia

An isolated IgA-mediated autoimmune hemolytic anemia can present a diagnostic challenge. When a routine direct antiglobulin test (DAT) is negative but clinical suspicion remains high, further testing with monospecific antisera should be performed. As with IgG-mediated WAIHA, steroids are first-line...

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Detalles Bibliográficos
Autores principales: Fetzko, Stephanie, Ahmed, Asra, Cooling, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405306/
https://www.ncbi.nlm.nih.gov/pubmed/25914813
http://dx.doi.org/10.1002/ccr3.203
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author Fetzko, Stephanie
Ahmed, Asra
Cooling, Laura
author_facet Fetzko, Stephanie
Ahmed, Asra
Cooling, Laura
author_sort Fetzko, Stephanie
collection PubMed
description An isolated IgA-mediated autoimmune hemolytic anemia can present a diagnostic challenge. When a routine direct antiglobulin test (DAT) is negative but clinical suspicion remains high, further testing with monospecific antisera should be performed. As with IgG-mediated WAIHA, steroids are first-line treatment, though splenectomy is often required to achieve a durable treatment response.
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spelling pubmed-44053062015-04-24 Finding the elusive and causative autoantibody: An atypical case of autoimmune hemolytic anemia Fetzko, Stephanie Ahmed, Asra Cooling, Laura Clin Case Rep Case Reports An isolated IgA-mediated autoimmune hemolytic anemia can present a diagnostic challenge. When a routine direct antiglobulin test (DAT) is negative but clinical suspicion remains high, further testing with monospecific antisera should be performed. As with IgG-mediated WAIHA, steroids are first-line treatment, though splenectomy is often required to achieve a durable treatment response. BlackWell Publishing Ltd 2015-04 2015-02-02 /pmc/articles/PMC4405306/ /pubmed/25914813 http://dx.doi.org/10.1002/ccr3.203 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Fetzko, Stephanie
Ahmed, Asra
Cooling, Laura
Finding the elusive and causative autoantibody: An atypical case of autoimmune hemolytic anemia
title Finding the elusive and causative autoantibody: An atypical case of autoimmune hemolytic anemia
title_full Finding the elusive and causative autoantibody: An atypical case of autoimmune hemolytic anemia
title_fullStr Finding the elusive and causative autoantibody: An atypical case of autoimmune hemolytic anemia
title_full_unstemmed Finding the elusive and causative autoantibody: An atypical case of autoimmune hemolytic anemia
title_short Finding the elusive and causative autoantibody: An atypical case of autoimmune hemolytic anemia
title_sort finding the elusive and causative autoantibody: an atypical case of autoimmune hemolytic anemia
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405306/
https://www.ncbi.nlm.nih.gov/pubmed/25914813
http://dx.doi.org/10.1002/ccr3.203
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