Successful treatment of immediate allogeneic myeloablative hematopoietic stem cell transplantation from a HLA-mismatched sibling donor for active systemic epstein–barr virus-positive T-cell lymphoproliferative disease of childhood following primary acute epstein–barr virus infection

A 22-year-old female was admitted for sustained high fever and diagnosed with systemic Epstein–Barr virus-positive T-cell lymphoproliferative disease. As her clinical course was so aggressive, she immediately underwent allogeneic myeloablative bone marrow transplantation from an HLA-mismatched sibli...

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Detalles Bibliográficos
Autores principales: Kakinoki, Yasutaka, Matsuoka, Satomi, Hashiguchi, Junichi, Chiba, Koji, Miyake, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405307/
https://www.ncbi.nlm.nih.gov/pubmed/25914814
http://dx.doi.org/10.1002/ccr3.204
Descripción
Sumario:A 22-year-old female was admitted for sustained high fever and diagnosed with systemic Epstein–Barr virus-positive T-cell lymphoproliferative disease. As her clinical course was so aggressive, she immediately underwent allogeneic myeloablative bone marrow transplantation from an HLA-mismatched sibling donor on hospital day 46. The patient has remained in complete remission for 3 years.

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