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Advanced Glycation End-Products Induce Apoptosis in Pancreatic Islet Endothelial Cells via NF-κB-Activated Cyclooxygenase-2/Prostaglandin E(2) Up-Regulation
Microvascular complications eventually affect nearly all patients with diabetes. Advanced glycation end-products (AGEs) resulting from hyperglycemia are a complex and heterogeneous group of compounds that accumulate in the plasma and tissues in diabetic patients. They are responsible for both endoth...
Autores principales: | Lan, Kuo-Cheng, Chiu, Chen-Yuan, Kao, Chia-Wei, Huang, Kuo-How, Wang, Ching-Chia, Huang, Kuo-Tong, Tsai, Keh-Sung, Sheu, Meei-Ling, Liu, Shing Hwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405342/ https://www.ncbi.nlm.nih.gov/pubmed/25898207 http://dx.doi.org/10.1371/journal.pone.0124418 |
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