Pro- and Anti-Inflammatory Cytokines against Rv2031 Are Elevated during Latent Tuberculosis: A Study in Cohorts of Tuberculosis Patients, Household Contacts and Community Controls in an Endemic Setting

Tuberculosis (TB) is among the leading causes of morbidity and mortality. The causative agent, Mycobacterium tuberculosis (Mtb), has evolved virulent factors for entry, survival, multiplication and immune evasion. Rv2031 (also called alpha crystallin, hspX, 16-kDa antigen), one of the most immunogen...

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Detalles Bibliográficos
Autores principales: Belay, Mulugeta, Legesse, Mengistu, Mihret, Adane, Bekele, Yonas, Ottenhoff, Tom H. M., Franken, Kees L. M. C., Bjune, Gunnar, Abebe, Fekadu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405476/
https://www.ncbi.nlm.nih.gov/pubmed/25897840
http://dx.doi.org/10.1371/journal.pone.0124134

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