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Alternative Splicing of SMPD1 in Human Sepsis

Acid sphingomyelinase (ASM or sphingomyelin phosphodiesterase, SMPD) activity engages a critical role for regulation of immune response and development of organ failure in critically ill patients. Beside genetic variation in the human gene encoding ASM (SMPD1), alternative splicing of the mRNA is in...

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Detalles Bibliográficos
Autores principales:	Kramer, Marcel, Quickert, Stefanie, Sponholz, Christoph, Menzel, Uwe, Huse, Klaus, Platzer, Matthias, Bauer, Michael, Claus, Ralf A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405572/ https://www.ncbi.nlm.nih.gov/pubmed/25898364 http://dx.doi.org/10.1371/journal.pone.0124503

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