A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress

Lung adenocarcinoma, the most common subtype of lung cancer, is the leading cause of cancer death worldwide. Despite attempts for the treatment of lung cancer which have been accumulating, promising new therapies are still needed. Here, we found that cyclic-AMP response element-binding protein (CREB...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Jong Woo, Park, Hee Sun, Park, Sin-Aye, Ryu, Seung-Hee, Meng, Wuyi, Jürgensmeier, Juliane M., Kurie, Jonathan M., Hong, Waun Ki, Boyer, Julie L., Herbst, Roy S., Koo, Ja Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405579/
https://www.ncbi.nlm.nih.gov/pubmed/25897662
http://dx.doi.org/10.1371/journal.pone.0122628

Ejemplares similares

Ejemplares similares