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Mapping the Interaction Sites between AMPA Receptors and TARPs Reveals a Role for the Receptor N-Terminal Domain in Channel Gating

AMPA-type glutamate receptors (AMPARs) mediate fast neurotransmission at excitatory synapses. The extent and fidelity of postsynaptic depolarization triggered by AMPAR activation are shaped by AMPAR auxiliary subunits, including the transmembrane AMPAR regulatory proteins (TARPs). TARPs profoundly i...

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Detalles Bibliográficos
Autores principales:	Cais, Ondrej, Herguedas, Beatriz, Krol, Karolina, Cull-Candy, Stuart G., Farrant, Mark, Greger, Ingo H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405707/ https://www.ncbi.nlm.nih.gov/pubmed/25373908 http://dx.doi.org/10.1016/j.celrep.2014.09.029

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