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The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon
BACKGROUND: The calcium sensing receptor (CaSR), a calcium-binding G protein-coupled receptor is expressed also in tissues not directly involved in calcium homeostasis like the colon. We have previously reported that CaSR expression is down-regulated in colorectal cancer (CRC) and that loss of CaSR...
Autores principales: | Aggarwal, Abhishek, Prinz-Wohlgenannt, Maximilian, Gröschel, Charlotte, Tennakoon, Samawansha, Meshcheryakova, Anastasia, Chang, Wenhan, Brown, Edward M, Mechtcheriakova, Diana, Kállay, Enikö |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405849/ https://www.ncbi.nlm.nih.gov/pubmed/25879211 http://dx.doi.org/10.1186/s12943-015-0330-4 |
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