Cargando…

MicroRNA-18a inhibits hypoxia-inducible factor 1α activity and lung metastasis in basal breast cancers

INTRODUCTION: In breast cancer, distinct expression profiles of microRNAs (miRNAs) have been associated with molecular subgroups and clinicopathological characteristics, implicating a diagnostic and prognostic role of miRNAs. However, the biological functions of deregulated miRNAs in tumor progressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krutilina, Raisa, Sun, Wenlin, Sethuraman, Aarti, Brown, Martin, Seagroves, Tiffany N, Pfeffer, Lawrence M, Ignatova, Tatyana, Fan, Meiyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405876/ https://www.ncbi.nlm.nih.gov/pubmed/25069832 http://dx.doi.org/10.1186/bcr3693

Ejemplares similares

BHLHE40 confers a pro-survival and pro-metastatic phenotype to breast cancer cells by modulating HBEGF secretion
por: Sethuraman, Aarti, et al.
Publicado: (2018)

ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models
por: Brooks, Danielle L. Peacock, et al.
Publicado: (2016)

SMARCE1 regulates metastatic potential of breast cancer cells through the HIF1A/PTK2 pathway
por: Sethuraman, Aarti, et al.
Publicado: (2016)

HIF-Dependent CKB Expression Promotes Breast Cancer Metastasis, Whereas Cyclocreatine Therapy Impairs Cellular Invasion and Improves Chemotherapy Efficacy
por: Krutilina, Raisa I., et al.
Publicado: (2021)

Sabizabulin, a Potent Orally Bioavailable Colchicine Binding Site Agent, Suppresses HER2+ Breast Cancer and Metastasis
por: Krutilina, Raisa I., et al.
Publicado: (2022)

SAT-133 Breast Tumor Kinase (Brk/PTK6) Mediates Triple Negative Breast Cancer Cell Migration and Taxol Resistance via SH2 Domain-Dependent Activation of RhoA and AhR
por: Dwyer, Amy Renee, et al.
Publicado: (2020)

Upregulation of the Oct3/4 Network in Basal Breast Cancer Is Associated with Its Metastatic Potential and Shows Tissue Dependent Variability
por: Rajan, Robin G., et al.
Publicado: (2023)

Correction: The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer
por: Fatima, Iram, et al.
Publicado: (2018)

MicroRNAs and Metastasis
por: Solé, Carla, et al.
Publicado: (2019)

Hypoxia-regulated microRNAs in human cancer
por: Shen, Guomin, et al.
Publicado: (2013)

Regulation of angiogenesis by hypoxia: the role of microRNA
por: Madanecki, Piotr, et al.
Publicado: (2012)

MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis
por: Qiu, Haijiang, et al.
Publicado: (2019)

Migrating leukocytes are the source of Peroxiredoxin V during inflammation in the airways
por: Krutilina, Raisa I, et al.
Publicado: (2006)

Exploring the Expression of Pro-Inflammatory and Hypoxia-Related MicroRNA-20a, MicroRNA-30e, and MicroRNA-93 in Periodontitis and Gingival Mesenchymal Stem Cells under Hypoxia
por: Chaparro, Alejandra, et al.
Publicado: (2022)

MicroRNAs in the Regulation of MMPs and Metastasis
por: Abba, Mohammed, et al.
Publicado: (2014)

Regulation of cancer metastasis by microRNAs
por: Chan, Shih-Hsuan, et al.
Publicado: (2015)

The role of microRNAs in bone metastasis
por: Zoni, Eugenio, et al.
Publicado: (2016)

MicroRNAs in cancer metastasis and angiogenesis
por: Lou, Weiyang, et al.
Publicado: (2017)

MicroRNA in Lung Cancer Metastasis
por: Wu, Shang-Gin, et al.
Publicado: (2019)

MicroRNAs in Metastasis and the Tumour Microenvironment
por: Solé, Carla, et al.
Publicado: (2021)

MicroRNA-18a promotes proliferation and metastasis in hepatocellular carcinoma via targeting KLF4
por: Liu, Li, et al.
Publicado: (2017)

Correlation of Global MicroRNA Expression With Basal Cell Carcinoma Subtype
por: Heffelfinger, Christopher, et al.
Publicado: (2012)

SRSF3 recruits DROSHA to the basal junction of primary microRNAs
por: Kim, Kijun, et al.
Publicado: (2018)

Genome-Wide Expression Difference of MicroRNAs in Basal Cell Carcinoma
por: Wei, Hai-Peng, et al.
Publicado: (2021)

Pivotal role for the ESCRT-II complex subunit EAP30/SNF8 in IRF3-dependent innate antiviral defense
por: Kumthip, Kattareeya, et al.
Publicado: (2017)

On the Importance of Host MicroRNAs During Viral Infection
por: Girardi, Erika, et al.
Publicado: (2018)

Hypoxia response and microRNAs: no longer two separate worlds
por: Ivan, Mircea, et al.
Publicado: (2008)

Hypoxia-Induced MicroRNA-210 Targets Neurodegenerative Pathways
por: Watts, Michelle E., et al.
Publicado: (2018)

MicroRNA expression profile during different conditions of hypoxia
por: Lacedonia, Donato, et al.
Publicado: (2018)

The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer
por: Fatima, Iram, et al.
Publicado: (2017)

MicroRNA Control of Invasion and Metastasis Pathways
por: Sreekumar, Rahul, et al.
Publicado: (2011)

Regulation of Metastasis by microRNAs in Ovarian Cancer
por: Wang, Yongchao, et al.
Publicado: (2014)

The roles of microRNAs in the regulation of tumor metastasis
por: Zhou, Lei, et al.
Publicado: (2015)

MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma
por: Sonkoly, E, et al.
Publicado: (2012)

Design of Effective Primary MicroRNA Mimics With Different Basal Stem Conformations
por: van den Berg, Fiona T, et al.
Publicado: (2016)

MicroRNAs as Molecular Biomarkers for the Characterization of Basal-like Breast Tumor Subtype
por: Tariq, Muhammad, et al.
Publicado: (2023)

MicroRNAs and Osteolytic Bone Metastasis: The Roles of MicroRNAs in Tumor-Induced Osteoclast Differentiation
por: Kagiya, Tadayoshi
Publicado: (2015)

Simultaneous Multi-Organ Metastases from Chemo-Resistant Triple-Negative Breast Cancer Are Prevented by Interfering with WNT-Signaling
por: Fatima, Iram, et al.
Publicado: (2019)

MicroRNA-22 Regulates Hypoxia Signaling in Colon Cancer Cells
por: Yamakuchi, Munekazu, et al.
Publicado: (2011)

MicroRNAs participate in the murine oligodendroglial response to perinatal hypoxia-ischemia
por: Birch, Derin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_kfuahimmtql2iep5s89k9g49ad