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Clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis

Clear cell odontogenic carcinoma (CCOC) is a rare aggressive tumor that has the ability to invade locally as well as cause regional and distant metastasis. The etiology of this neoplasm remains poorly understood and the diagnosis of CCOC is done by exclusion of other clear cell tumors. To date, appr...

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Autores principales: Krishnamurthy, Arvind, Ramshankar, Vijayalakshmi, Majhi, Urmila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405972/
https://www.ncbi.nlm.nih.gov/pubmed/25937741
http://dx.doi.org/10.4103/0975-5950.154842
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author Krishnamurthy, Arvind
Ramshankar, Vijayalakshmi
Majhi, Urmila
author_facet Krishnamurthy, Arvind
Ramshankar, Vijayalakshmi
Majhi, Urmila
author_sort Krishnamurthy, Arvind
collection PubMed
description Clear cell odontogenic carcinoma (CCOC) is a rare aggressive tumor that has the ability to invade locally as well as cause regional and distant metastasis. The etiology of this neoplasm remains poorly understood and the diagnosis of CCOC is done by exclusion of other clear cell tumors. To date, approximately 75 cases of CCOC have been described in the English literature, all involving a single jaw. The majority of cases have been reported to arise from the mandible, the maxilla is less frequently involved, and no case had involvement of the temporomandibuar joint. Lymph node metastasis at initial presentation is reportedly rare (<10%). We describe possibly the first case of CCOC in a 50-year-old woman with involvement of the mandible and the temporomandibuar joint along with cervical lymph nodal metastasis. We share our experiences and challenges in the management of this unusual tumor.
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spelling pubmed-44059722015-05-01 Clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis Krishnamurthy, Arvind Ramshankar, Vijayalakshmi Majhi, Urmila Natl J Maxillofac Surg Case Report Clear cell odontogenic carcinoma (CCOC) is a rare aggressive tumor that has the ability to invade locally as well as cause regional and distant metastasis. The etiology of this neoplasm remains poorly understood and the diagnosis of CCOC is done by exclusion of other clear cell tumors. To date, approximately 75 cases of CCOC have been described in the English literature, all involving a single jaw. The majority of cases have been reported to arise from the mandible, the maxilla is less frequently involved, and no case had involvement of the temporomandibuar joint. Lymph node metastasis at initial presentation is reportedly rare (<10%). We describe possibly the first case of CCOC in a 50-year-old woman with involvement of the mandible and the temporomandibuar joint along with cervical lymph nodal metastasis. We share our experiences and challenges in the management of this unusual tumor. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4405972/ /pubmed/25937741 http://dx.doi.org/10.4103/0975-5950.154842 Text en Copyright: © National Journal of Maxillofacial Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Krishnamurthy, Arvind
Ramshankar, Vijayalakshmi
Majhi, Urmila
Clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis
title Clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis
title_full Clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis
title_fullStr Clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis
title_full_unstemmed Clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis
title_short Clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis
title_sort clear cell odontogenic carcinoma of the mandible and temporomandibuar joint with cervical lymph nodal metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405972/
https://www.ncbi.nlm.nih.gov/pubmed/25937741
http://dx.doi.org/10.4103/0975-5950.154842
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