Cargando…
An ace up their sleeve: a transcriptomic approach exposes the AceI efflux protein of Acinetobacter baumannii and reveals the drug efflux potential hidden in many microbial pathogens
The era of antibiotics as a cure-all for bacterial infections appears to be coming to an end. The emergence of multidrug resistance in many hospital-associated pathogens has resulted in “superbugs” that are effectively untreatable. Multidrug efflux pumps are well known mediators of bacterial drug resi...
Autores principales: | Hassan, Karl A., Elbourne, Liam D. H., Li, Liping, Gamage, Hasinika K. A. H., Liu, Qi, Jackson, Scott M., Sharples, David, Kolstø, Anne-Brit, Henderson, Peter J. F., Paulsen, Ian T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406071/ https://www.ncbi.nlm.nih.gov/pubmed/25954261 http://dx.doi.org/10.3389/fmicb.2015.00333 |
Ejemplares similares
-
Regulation of the aceI multidrug efflux pump gene in Acinetobacter baumannii
por: Liu, Qi, et al.
Publicado: (2018) -
Homologs of the Acinetobacter baumannii AceI Transporter Represent a New Family of Bacterial Multidrug Efflux Systems
por: Hassan, Karl A., et al.
Publicado: (2015) -
Assembly and regulation of the chlorhexidine-specific efflux pump AceI
por: Bolla, Jani Reddy, et al.
Publicado: (2020) -
Inhibition of AdeB, AceI, and AmvA Efflux Pumps Restores Chlorhexidine and Benzalkonium Susceptibility in Acinetobacter baumannii ATCC 19606
por: Migliaccio, Antonella, et al.
Publicado: (2022) -
The putative drug efflux systems of the Bacillus cereus group
por: Hassan, Karl A., et al.
Publicado: (2017)