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BioMiner: Paving the Way for Personalized Medicine

Personalized medicine is promising a revolution for medicine and human biology in the 21st century. The scientific foundation for this revolution is accomplished by analyzing biological high-throughput data sets from genomics, transcriptomics, proteomics, and metabolomics. Currently, access to these...

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Detalles Bibliográficos
Autores principales: Bauer, Chris, Stec, Karol, Glintschert, Alexander, Gruden, Kristina, Schichor, Christian, Or-Guil, Michal, Selbig, Joachim, Schuchhardt, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406277/
https://www.ncbi.nlm.nih.gov/pubmed/26005322
http://dx.doi.org/10.4137/CIN.S20910
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author Bauer, Chris
Stec, Karol
Glintschert, Alexander
Gruden, Kristina
Schichor, Christian
Or-Guil, Michal
Selbig, Joachim
Schuchhardt, Johannes
author_facet Bauer, Chris
Stec, Karol
Glintschert, Alexander
Gruden, Kristina
Schichor, Christian
Or-Guil, Michal
Selbig, Joachim
Schuchhardt, Johannes
author_sort Bauer, Chris
collection PubMed
description Personalized medicine is promising a revolution for medicine and human biology in the 21st century. The scientific foundation for this revolution is accomplished by analyzing biological high-throughput data sets from genomics, transcriptomics, proteomics, and metabolomics. Currently, access to these data has been limited to either rather simple Web-based tools, which do not grant much insight or analysis by trained specialists, without firsthand involvement of the physician. Here, we present the novel Web-based tool “BioMiner,” which was developed within the scope of an international and interdisciplinary project (SYSTHER) and gives access to a variety of high-throughput data sets. It provides the user with convenient tools to analyze complex cross-omics data sets and grants enhanced visualization abilities. BioMiner incorporates transcriptomic and cross-omics high-throughput data sets, with a focus on cancer. A public instance of BioMiner along with the database is available at http://systherDB.microdiscovery.de/, login and password: “systher”; a tutorial detailing the usage of BioMiner can be found in the Supplementary File.
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spelling pubmed-44062772015-05-22 BioMiner: Paving the Way for Personalized Medicine Bauer, Chris Stec, Karol Glintschert, Alexander Gruden, Kristina Schichor, Christian Or-Guil, Michal Selbig, Joachim Schuchhardt, Johannes Cancer Inform Technical Advance Personalized medicine is promising a revolution for medicine and human biology in the 21st century. The scientific foundation for this revolution is accomplished by analyzing biological high-throughput data sets from genomics, transcriptomics, proteomics, and metabolomics. Currently, access to these data has been limited to either rather simple Web-based tools, which do not grant much insight or analysis by trained specialists, without firsthand involvement of the physician. Here, we present the novel Web-based tool “BioMiner,” which was developed within the scope of an international and interdisciplinary project (SYSTHER) and gives access to a variety of high-throughput data sets. It provides the user with convenient tools to analyze complex cross-omics data sets and grants enhanced visualization abilities. BioMiner incorporates transcriptomic and cross-omics high-throughput data sets, with a focus on cancer. A public instance of BioMiner along with the database is available at http://systherDB.microdiscovery.de/, login and password: “systher”; a tutorial detailing the usage of BioMiner can be found in the Supplementary File. Libertas Academica 2015-04-20 /pmc/articles/PMC4406277/ /pubmed/26005322 http://dx.doi.org/10.4137/CIN.S20910 Text en © 2015 the authors, publisher and licensee Libertas Academica Limited. This is an open-access article distributed under the terms of the Creative Commons CC-BY-NC 3.0 License.
spellingShingle Technical Advance
Bauer, Chris
Stec, Karol
Glintschert, Alexander
Gruden, Kristina
Schichor, Christian
Or-Guil, Michal
Selbig, Joachim
Schuchhardt, Johannes
BioMiner: Paving the Way for Personalized Medicine
title BioMiner: Paving the Way for Personalized Medicine
title_full BioMiner: Paving the Way for Personalized Medicine
title_fullStr BioMiner: Paving the Way for Personalized Medicine
title_full_unstemmed BioMiner: Paving the Way for Personalized Medicine
title_short BioMiner: Paving the Way for Personalized Medicine
title_sort biominer: paving the way for personalized medicine
topic Technical Advance
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406277/
https://www.ncbi.nlm.nih.gov/pubmed/26005322
http://dx.doi.org/10.4137/CIN.S20910
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