Serpine2/PN-1 Is Required for Proliferative Expansion of Pre-Neoplastic Lesions and Malignant Progression to Medulloblastoma

BACKGROUND: Medulloblastomas are malignant childhood brain tumors that arise due to the aberrant activity of developmental pathways during postnatal cerebellar development and in adult humans. Transcriptome analysis has identified four major medulloblastoma subgroups. One of them, the Sonic hedgehog...

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Detalles Bibliográficos
Autores principales: Vaillant, Catherine, Valdivieso, Paola, Nuciforo, Sandro, Kool, Marcel, Schwarzentruber-Schauerte, Alexandra, Méreau, Hélène, Cabuy, Erik, Lobrinus, Johannes A., Pfister, Stefan, Zuniga, Aimée, Frank, Stephan, Zeller, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406471/
https://www.ncbi.nlm.nih.gov/pubmed/25901736
http://dx.doi.org/10.1371/journal.pone.0124870

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