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Repurposing Drugs in Oncology (ReDO)—itraconazole as an anti-cancer agent
Itraconazole, a common triazole anti-fungal drug in widespread clinical use, has evidence of clinical activity that is of interest in oncology. There is evidence that at the clinically relevant doses, itraconazole has potent anti-angiogenic activity, and that it can inhibit the Hedgehog signalling p...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cancer Intelligence
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406527/ https://www.ncbi.nlm.nih.gov/pubmed/25932045 http://dx.doi.org/10.3332/ecancer.2015.521 |