Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile

Primordial germ cells (PGCs) develop only into sperm and oocytes in vivo. The molecular mechanisms underlying human PGC specification are poorly understood due to inaccessibility of cell materials and lack of in vitro models for tracking the earliest stages of germ cell development. Here, we describ...

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Detalles Bibliográficos
Autores principales: Sugawa, Fumihiro, Araúzo-Bravo, Marcos J, Yoon, Juyong, Kim, Kee-Pyo, Aramaki, Shinya, Wu, Guangming, Stehling, Martin, Psathaki, Olympia E, Hübner, Karin, Schöler, Hans R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406649/
https://www.ncbi.nlm.nih.gov/pubmed/25750208
http://dx.doi.org/10.15252/embj.201488049

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