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Cathepsin K knockout alleviates aging-induced cardiac dysfunction

Aging is a major risk factor for cardiovascular disease. It has previously been shown that protein levels of cathepsin K, a lysosomal cysteine protease, are elevated in the failing heart and that genetic ablation of cathepsin K protects against pressure overload-induced cardiac hypertrophy and contr...

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Detalles Bibliográficos
Autores principales:	Hua, Yinan, Robinson, Timothy J, Cao, Yongtao, Shi, Guo-Ping, Ren, Jun, Nair, Sreejayan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406663/ https://www.ncbi.nlm.nih.gov/pubmed/25692548 http://dx.doi.org/10.1111/acel.12276

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