Stn1 is critical for telomere maintenance and long-term viability of somatic human cells

Disruption of telomere maintenance pathways leads to accelerated entry into cellular senescence, a stable proliferative arrest that promotes aging-associated disorders in some mammals. The budding yeast CST complex, comprising Cdc13, Stn1, and Ctc1, is critical for telomere replication, length regul...

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Detalles Bibliográficos
Autores principales: Boccardi, Virginia, Razdan, Neetu, Kaplunov, Jessica, Mundra, Jyoti J, Kimura, Masayuki, Aviv, Abraham, Herbig, Utz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406666/
https://www.ncbi.nlm.nih.gov/pubmed/25684230
http://dx.doi.org/10.1111/acel.12289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406666/
https://www.ncbi.nlm.nih.gov/pubmed/25684230
http://dx.doi.org/10.1111/acel.12289

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