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Global analyses revealed age-related alterations in innate immune responses after stimulation of pathogen recognition receptors

Aging leads to dysregulation of multiple components of the immune system that results in increased susceptibility to infections and poor response to vaccines in the aging population. The dysfunctions of adaptive B and T cells are well documented, but the effect of aging on innate immunity remains in...

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Detalles Bibliográficos
Autores principales:	Metcalf, Talibah U, Cubas, Rafael A, Ghneim, Khader, Cartwright, Michael J, Grevenynghe, Julien Van, Richner, Justin M, Olagnier, David P, Wilkinson, Peter A, Cameron, Mark J, Park, Byung S, Hiscott, John B, Diamond, Michael S, Wertheimer, Anne M, Nikolich-Zugich, Janko, Haddad, Elias K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406671/ https://www.ncbi.nlm.nih.gov/pubmed/25728020 http://dx.doi.org/10.1111/acel.12320

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